BP104TP : Pharmaceutical inorganic chemistry

Unit_01 :

Syllabus

Impurities in pharmaceutical substances : History of pharmacopoeia, sources and types of impurities, principles involved in the limits test for chloride, sulphate, Iron, Arsenic, Lead and Heavy metals, modified limit test for chloride and sulphate
General methods of preparation, assay for the compounds superscripted with asterisk (*), properties and medicinal uses of inorganic compounds belonging to the following classes

Syllabus

Acids, Bases and buffers : Buffers equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculation and methods of adjusting isotonicity.
Major extra and intracellular electrolytes : Functions of major physiological ions, Electrolytes used in the replacement therapy: Sodium chloride* , Potassium chloride, calcium gluconate* and Oral Rehydration Salt (ORS), Physiological acid base balance.
Dental Products : Dentifrices, role of fluoride in the treatment of dental caries, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement.

Syllabus

Gastrointestinal agents
Acidifiers : Ammonium chloride* and Dil. HCl
Antacid : Ideal properties of antacids, combination of antacids, sodium Bicarbonate* , Aluminium hydroxide gel, Magnesium hydroxide mixture
Cathartics : Magnesium, classification, Sodium orthophosphate, kaolin and bentonite
Antimicrobes : Mechanism, classification, potassium permanganate, Boric acid, Hydrogen peroxide*, Chlorinated lime*, Iodine and its preparations

Syllabus

Miscellaneous compounds
Expectorants : Potassium Iodide, Ammonium chloride*
Emetics : Copper sulphate*, Sodium potassium tartarate
Haematinics : Ferrous sulphate*, Ferrous gluconate
Posion and Antidote : Sodium thiosulphate* , Activated charcoal, sodium nitrate333
Astringent : Zinc sulphate, Potash Alum

Syllabus

Radiopharmaceuticals : Radio activity, Measurements of radioactivity, Properties of Alpha, beta, gema radiations, Half life, radio isotopes and study of radio isotopes – Sodium iodide 1131, Storage condition, precautions & Pharmaceutical application of radioactive substance.